The Pathways Active Study Page
This section encompasses study specific tools and videos for your reference. If you have any questions, comments, or new ideas please contact NCRAD by email or phone (800) 526-2839 or directly at (317) 278-1170.
Specimen Collection Overview
Collection Tube
|
Drawn At
|
Specimen Type
|
Aliquot Volume
|
Total Number of Aliquots
|
Shipping Temperature
|
---|---|---|---|---|---|
1 EDTA (Purple Top) Blood Collection Tube (10 ml) |
All Visits |
Plasma |
1.5 ml plasma aliquot |
Up to 4 |
Frozen |
0.5 ml plasma aliquot |
1 |
Kept locally at site |
|||
Buffy Coat |
1.0 ml buffy coat aliquot |
1 |
Frozen |
Specimen Packaging Configuration
A 25-cell cryobox should contain samples from 3 participant visits. Each participant visit will have up to 4 x Plasma Aliquots and 1 x Buffy Coat Aliquot. This means there should be 12-15 samples per cryobox (9-12 x plasma aliquots and 3 x buffy coat aliquots). An individual participant's samples should be placed in a single row. An empty row should separate each participant's samples from another participant's samples. Plasma samples should be placed to the left, with the buffy coat sample immediately to the right of the last plasma sample. Up to 8 cryoboxes can be put in each shipper.
Study Resources
Kit Request Module
Please follow the below link to access the Kit Request Module. This link will direct you to a REDCap database where study coordinators and staff may request kits, individual supplies, and/or labels. Study related sites will use the same link for ordering supplies related to blood-based samples and for CSF. Please allow a total of two weeks for kit requests to be compiled and delivered to your site.
Kit Request SystemManual of Procedures
The below downloadable manual for biomarkers was created specifically for the Pathways Study. Please feel free to explore the manuals through the hyperlinked “Table of Contents”. Questions concerning any part of the manual may be directed to NCRAD at (alzstudy@iu.edu, 800-526-2839 or 317-274-7546) for further clarification.
Manual of ProceduresStudy Related Video Tutorials
Frozen Shipping
Plasma
Training Slides
Please see the link below for the training slides for the study.
Training Slides